Author

Federica Fratini

Istituto Superiore di SanitàORCID 0000-0003-0807-930XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Alessandro NotoiD· 1 shared Annapaola FranchittoiD· 1 shared Benedetta Perdichizzi· 1 shared Flavia Di Feo· 1 shared Joshua A. SommersiD· 1 shared Marco CrescenziiD· 1 shared Maurizio Semproni· 1 shared Pasquale ValenzisiiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Alessandro NotoORCID

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1 paper

Recent·Most cited

Cell BiologyNature CommunicationsPeer-reviewedJan 27, 2025

PHOSPHORYLATION-DEPENDENT ASSOCIATION OF WRN WITH RPA IS REQUIRED FOR RECOVERY OF REPLICATION FORKS STALLED AT SECONDARY DNA STRUCTURES

Alessandro Noto, Pasquale Valenzisi, Flavia Di Feo…·Pietro Pichierri

This study shows that phosphorylation-dependent WRN-RPA interaction is essential for replication fork recovery after stalling at secondary DNA structures, preventing DNA damage and G4 accumulation.

19 citationstop 5%

humanexperimental assay

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