Author

Stephen Clarke

Vanderbilt UniversityORCID 0000-0003-0830-1388Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Research Focus:protein structure prediction· 2 Assay:proteomics· 2

Frequent Co-Authors

Manuel AscanoiD· 4 shared Andrea AscuraiD· 2 shared Samantha M. LisyiD· 2 shared Alissa M. WeaveriD· 1 shared Andrew F. Livingston· 1 shared Bahnisikha BarmaniD· 1 shared Caroline L. WiseriD· 1 shared D. PateliD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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4 shared papersMolecular Biology

Manuel AscanoORCID

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Author profile →

4 papers

Recent·Most cited

Fatty Acid Synthase Binds Cellular mRNAs and its Depletion Reduces Translational Efficiency

Yelena Perevalova-Pinzul, James Marks, Marcin Piotr Sajek, Stephen Clarke, Samantha Lisy, Neelanjan Mukherjee, Sezen Meydan, Manuel Ascano

This study identifies FASN's RNA binding sites and shows its depletion reduces translational efficiency of associated mRNAs.

bioRxiv · Nov 7, 2026 · PreprintMolecular Biology

Extracellular vesicle cross-linking coupled with solid-phase purification facilitates discovery of ribonucleoprotein complexes assembled on EV RNAs.

Rajat Dhyani, Stephen Clarke, Masashi Kuroda, Yohei Sanada, Marc Gorum, Bahnisikha Barman, Alissa M. Weaver, Takahisa Nakamura, Manuel Ascano

This paper introduces two methods, EV-CLASP and EV(r)-CLASP, to study RNP complexes on EV RNAs, revealing post-transfer interactions and intra-vesicular compositions.

bioRxiv · Oct 6, 2026 · PreprintCancer Biology

The Incoming Influenza Genome Assembles a Host RBP Network that Orchestrates Viral RNA Synthesis

Stephen Clarke, D. Patel, Andrea Ascura, Caroline L. Wiser, Jennifer L Pennise, Samantha M. Lisy, Manuel Ascano

The paper identifies host RNA binding proteins interacting with incoming influenza virus RNA and shows their roles in viral replication.

bioRxiv · Dec 11, 2025 · PreprintMolecular Biology

Early Host-Virus RNA Interactions Reveal SPEN-Driven m6A Regulation as a Major Determinant of Henipavirus Infection

Andrea Ascura, Stephen Clarke, Andrew F. Livingston, Jackson B. Trotman, Sander Haigh, Morad C. Malek, J. Mauro Calabrese, Manuel Ascano

The paper identifies SPEN-driven m6A regulation as a key factor in henipavirus infection by analyzing host-virus RNA interactions using VIR-CLASP.

bioRxiv · Nov 21, 2025 · PreprintBiochemistry