Alissa M. Weaver

This paper introduces two methods, EV-CLASP and EV(r)-CLASP, to study RNP complexes on EV RNAs, revealing post-transfer interactions and intra-vesicular compositions.

This study investigates how fluid shear stress affects the uptake and junctional targeting of tumor-derived extracellular vesicles by endothelial cells, identifying clathrin- and caveolin-mediated endocytosis as key pathways.

This study identifies SEV cargoes associated with lymph node metastasis in HNSCC using proteomic profiling and mouse models, showing their potential as biomarkers and functional mediators.

This study identifies exosomes carrying THSD7A as regulators of filopodia formation in both cancer cells and neurons, mediated through Cdc42 activation.

This study shows that exosomes initiate fibronectin assembly in vitro and in vivo, reducing tumor growth and fibrosis.

This study shows that macromolecular diABZI conjugates activate STING in vitro and in vivo, with similar potency to small molecule agonists, suggesting new strategies for STING agonist delivery.

This study identifies miR-100 and miR-125b as regulators of 3D growth and invasiveness in cancer cells, showing they can be transferred extracellularly to silence target genes in recipient cells.

This study shows that 5-FU treatment alters the export and base modifications of small RNAs in extracellular vesicles from colorectal cancer cells.

This study shows SCLC cells exist in a continuum of plastic states rather than discrete subtypes, with gene expression patterns linked to cancer hallmarks and potential therapeutic targets.