Elen Tolstik

The paper develops a multimodal imaging approach combining Raman and AP-MALDI MSI to detect Gb3 accumulation in cardiac tissue of Fabry disease mouse models.

NO2-OA treatment improves diastolic dysfunction in HFpEF mice by enhancing mitochondrial biogenesis and oxidative phosphorylation.

This study shows that thyroid hormone-induced cardiac hypertrophy relies on noncanonical TR action, while heart rate regulation depends on canonical TR action, with TRβ compensating for TR absence.