ImmunologyFASEB BioAdvancesPeer-reviewed
Human inborn errors of long-chain fatty acid oxidation show impaired inflammatory responses to TLR4-ligand LPS
Signe Mosegaard, Krishna S. Twayana, Simone W. Denis…·Christian Kanstrup Holm
This study shows that mutations in ETFDH and ACADVL, which are involved in long-chain fatty acid oxidation, impair inflammatory responses to LPS by reducing TLR4 expression and cytokine production.
5 citations