Xincheng Xu

The paper investigates how high-fat circulating nutrients affect tumor growth and invasion in a 3D microfluidic model of triple-negative breast cancer, finding increased metabolic activity and MMP1 expression.

This study investigates the effect of dietary fiber on immune checkpoint blockade efficacy in murine tumor models and finds inconsistent results across different models.

This study shows that supplementing one-carbon units enhances anti-PD-1 checkpoint blockade by supporting purine synthesis in tumor-infiltrating T cells, leading to increased durable tumor regression.