Author
Queen Mary University of LondonORCID 0000-0003-1126-897XUnclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Molly A Guscott, Audrey Lumeau, A. Gallagher…·Sarah Elizabeth McClelland
This study shows that chromosomal instability (CIN) drives rapid genome changes in cancer cells, generating new copy number alterations each cell cycle and increasing genomic complexity.
Elizabeth Proaño-Pérez, Eva Serrano‐Candelas, Mario Guerrero…·Margarita Martı́n
This study identifies MITF-regulated genes in GIST, showing its role in autophagy and extracellular vesicle secretion, with implications for tumor growth and metastasis.
Molly A Guscott, David Gómez-Peregrina, Alexander Malling Andersen…·Sarah Elizabeth McClelland
The paper tracks genome evolution in single-cell clones to reveal copy number alteration rates and features in cancer driven by chromosomal instability.