Author

Sami Chaaban

MRC Laboratory of Molecular BiologyORCID 0000-0003-1133-800XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Cell Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:Arabidopsis· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:comparative / phylogenetic analysis· 1 Organism:Drosophila· 1

Frequent Co-Authors

Andrew P. CarteriD· 3 shared Ahmet YıldıziD· 1 shared Alessio VagnoniiD· 1 shared Andrew M. HensleyiD· 1 shared Aurélien RouxiD· 1 shared Buzz BaumiD· 1 shared David Salvador-GarciaiD· 1 shared Diorge Paulo de SouzaiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersMolecular Biology

Andrew P. CarterORCID

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4 papers

Recent·Most cited

Molecular BiologybioRxivPreprintApr 28, 2026

Structural basis of dynein interaction with diverse activating adaptors

Ennio A. d’Amico, Sami Chaaban, Ferdos Abid Ali…·Andrew P. Carter

This study determines cryo-EM structures of dynein-dynactin complexes with five adaptors, revealing shared activation mechanisms and adaptor-specific structural features.

2 citations

experimental assay

𝕏 PostBluesky

Evolutionary BiologyScience AdvancesPeer-reviewedFeb 7, 2025

Evolutionarily conserved principles of ESCRT-III-mediated membrane remodelling revealed by a two-subunit Asgard archaeal system

Diorge Paulo de Souza, Javier Espadas, Sami Chaaban…·Buzz Baum

The paper identifies evolutionarily conserved principles of ESCRT-III-mediated membrane remodeling using an Asgard archaeal two-subunit system, showing homology to eukaryotic ESCRT-IIIB and IIIA.

29 citationstop 1%

Arabidopsiscomparative / phylogenetic analysis

𝕏 PostBluesky

Cell BiologyThe Journal of Cell BiologyPeer-reviewedJun 19, 2024

A force-sensitive mutation reveals a spindle assembly checkpoint-independent role for dynein in anaphase progression

David Salvador-Garcia, Li Jin, Andrew M. Hensley…·Simon L. Bullock

This study identifies a mutation in dynein that causes mitotic spindle arrest independent of the spindle assembly checkpoint, revealing a load-dependent role in anaphase progression.

7 citations

Drosophilaexperimental assay

𝕏 PostBluesky

Molecular BiologybioRxivPreprintMar 17, 2022

Structure of dynein-dynactin on microtubules shows tandem recruitment of cargo adaptors

Sami Chaaban, Andrew P. Carter

The paper determines the structure of dynein-dynactin complex with BICDR1 adaptor bound to microtubules, revealing adaptor recruitment mechanism and interactions.

9 citations

experimental assay

𝕏 PostBluesky