Author

Nathan R. James

MRC Laboratory of Molecular BiologyORCID 0000-0003-1147-6285Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Aiwei ZengiD· 2 shared Andrei MihutiD· 2 shared Andrew D. BealeiD· 2 shared John Stuart O'NeilliD· 2 shared Alejandra GoityiD· 1 shared Alessandra StangherliniD· 1 shared Antony N. DoddiD· 1 shared Aymen al-RawiiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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2 shared papersCell Biology

Aiwei ZengORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintOct 30, 2026

mTOR signalling, not clock gene rhythms, organises daily physiology

Aiwei Zeng, Andrei Mihut, Madhanagopal Anandapadamanaban…·John Stuart O'Neill

This study shows that mTOR signalling, not clock gene rhythms, drives daily physiological variations in mammals and plants.

DOI 10.64898/2026.08.28.747564

𝕏 PostBluesky

Cell BiologybioRxivPreprintJun 22, 2023

A cellular basis for the mammalian nocturnal-diurnal switch

Andrew D. Beale, Nina M. Rzechorzek, Andrei Mihut…·John S. O’Neill

The paper identifies a conserved cell-intrinsic signal inversion that enables the transition from nocturnality to diurnality, with mTOR signaling as a central mediator.

DOI 10.1101/2023.06.22.546020

𝕏 PostBluesky