Author

Mingzhen Fan

University of ZurichORCID 0000-0003-1261-9217Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:Drosophila· 1 Organism:human· 1

Frequent Co-Authors

Hubert HilbiiD· 2 shared Jürgen SeibeliD· 2 shared Paul Charki· 2 shared Ana Katic· 1 shared Christian HedbergiD· 1 shared François LetourneuriD· 1 shared Franziska Solger· 1 shared Jonas Rauch· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersMicrobiology

Hubert HilbiORCID

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2 papers

Recent·Most cited

MicrobiologyPLoS PathogensPeer-reviewedApr 29, 2025

Inter-kingdom signaling by the Legionella autoinducer LAI-1 involves the antimicrobial guanylate binding protein GBP

Franziska Solger, Jonas Rauch, Simone Vormittag…·Hubert Hilbi

This study shows LAI-1, a signaling molecule from Legionella pneumophila, interacts with GBP in D. discoideum to inhibit migration and restrict bacterial growth.

2 citations

Drosophilaexperimental assay

𝕏 PostBluesky

MicrobiologyJournal of Biological ChemistryPeer-reviewedOct 20, 2023

The Legionella autoinducer LAI-1 is delivered by outer membrane vesicles to promote inter-bacterial and inter-kingdom signaling

Mingzhen Fan, Patrick Kiefer, Paul Charki…·Hubert Hilbi

This paper identifies LAI-1 as a signaling molecule secreted by Legionella pneumophila via outer membrane vesicles, promoting inter-bacterial and inter-kingdom communication.

11 citations

humanexperimental assay

𝕏 PostBluesky