Hendrik Dietz

This paper describes a system using DNA origami to control directional membrane budding, mimicking virus assembly and producing DNA-shelled vesicles with applications in drug delivery and synthetic biology.

This paper introduces a protein design pipeline using AlphaFold2 and ProteinMPNN to refine large de novo protein backbones, improving structural integrity and designability.

This study uses DNA origami nanoshells to neutralize hepatitis B virus in cell culture by trapping the virus and enhancing antibody effectiveness through multivalent binding and physical barriers.

This study demonstrates DNA origami can be directed in vivo to target immune cells and cancer metastases, showing potential for precision drug delivery.

This paper introduces a method for efficient de novo protein design using a relaxed sequence space approach, demonstrating successful experimental production of over 50 proteins with desired structural properties.

The paper introduces a genetic iron-biomineralizing nanocompartment for multiplexed EM gene reporter imaging in mammalian cells.