Hopi E. Hoekstra

The paper identifies two genes within a chromosomal inversion supergene in deer mice that contribute to forest adaptation traits and shows the supergene evolved through sequential allele accumulation.

This study constructs a pangenome for deer mice to reveal extensive structural variation and its evolutionary implications.

This study identifies a genetic locus and cerebellar mechanisms influencing neonatal cry duration in deer mice, linking cerebellar anatomy and function to vocal behavior variation.

This study shows Pleistocene climate changes drove the diversification of deer mice and the independent evolution of arboreal ecotypes in forests.

This study shows that forest mice have larger corticospinal tracts and greater dexterity compared to prairie mice, supporting the hypothesis that CSN number expansion enhances motor skills.

This study examines chromosomal inversions and demographic history in deer mice populations across islands and mainland, finding shared balancing selection and ancient divergence.

This study analyzes the olfactory genome of deer mice to reveal conserved and divergent components of the rodent olfactory subgenome and their evolutionary implications.

The paper builds a cellular atlas of the hypothalamic preoptic area in two deer mouse species, identifying cell types linked to behavioral differences and sex-specific evolution.

This study identifies thousands of chromosomal inversions in deer mice and shows that repeats, particularly centromeric satellite arrays, drive large-scale genomic rearrangements.

This paper identifies genetic and developmental mechanisms underlying tail-length variation in deer mice, showing Hoxd13 expression differences and increased presomitic mesoderm in forest ecotypes.

This study examines gene expression differences across brain regions in two deer mouse species and their hybrids, finding widespread interspecific variation and regional modularity in gene regulation.

This study identifies species-specific escape thresholds in Peromyscus mice by analyzing neural circuits in the dorsal periaqueductal gray.

This study identifies a genetic locus that increases burrow length in deer mice by altering specific digging behaviors.

The paper examines the unique TE landscape in deer mice, showing LTR retrotransposons dominate over LINEs due to ERV invasion and KZNF gene expansion.

The paper identifies Tug1 as essential for male fertility, showing it has three distinct regulatory activities: a cis DNA repressor, a trans-acting lncRNA, and a conserved peptide affecting mitochondrial function.

The paper investigates how genetic variation in wild mice affects fitness by linking genotype to phenotype and allele frequency changes through field and lab experiments.

This study investigates the genetic basis of spiny hair evolution in rodents, finding that a specific Edar mutation associated with human hair variation is not linked to spiny hair in rodents.