Victoria Meliopoulos

This study shows that H5N1 clade 2.3.4.4b influenza virus can infect mice via intraductal inoculation, suggesting a potential new transmission route and a model for studying mammary gland infections.

This study compares the replication ability of avian and mammalian-derived clade 2.3.4.4b H5N1 viruses in epithelial cells from different species, finding that mammalian strains replicate more broadly.

The paper shows that pre-existing immunity from H1N1 infection or vaccination can protect against lethal HPAI H5N1 clade 2.3.4.4b challenge in mice and ferrets, independent of hemagglutination inhibition titers.

This study investigates the effects of oral exposure to pasteurized HPAI H5N1 virus in milk on immune response and mortality in mice, finding limited health risk and no prevention of immune-mediated protection.

This study investigates how host obesity affects genetic variation in influenza A virus populations using a ferret model, finding enhanced positive selection and host-specific mutations in obese hosts.

This study shows diet-induced obesity in ferrets increases influenza disease severity and transmission due to altered lung microenvironment and reduced antiviral responses.

This study compares antibody profiles from maternal influenza vaccines in mice, showing LAIV and rHA provide better offspring protection than TIV.

This study shows that beta 6 integrin suppresses TLR7-mediated epithelial immunity during influenza A virus infection by promoting autophagy and altering TLR7 trafficking.