Weiguo Cui

This study shows that PIM1 in macrophages enhances CD36 expression and function, promoting foam cell formation and atherosclerosis, and that targeting this pathway could reduce plaque progression.

This study shows that stromal gasdermin D-mediated pyroptosis promotes CD4⁺ T-cell remodeling in Tet2-deficient hematopoiesis by creating a feedback loop between stromal cells and immune cells.

The paper identifies divergent macrophage-regulated T cell states in BCG responders and non-responders in high-risk bladder cancer, linking them to immune response outcomes.

This study shows that anti-CD49d antibody treatment reduces age-related inflammatory responses and CD8 T cell cytotoxicity after traumatic brain injury in mice.

This study shows that CB2R on microglia drives neuroinflammation in GVHD by promoting T cell activation and neuronal death, and that targeting CB2R reduces inflammation without worsening systemic GVHD.

This study identifies the CD36-PKM2-mtROS pathway as a mechanism by which oxidized LDL disrupts efferocytosis, contributing to atherosclerosis progression.