Hyung Bum Kim

This study benchmarks and optimizes Perturb-seq in human pluripotent stem cells, identifying shared regulatory networks during cardiomyocyte differentiation.

The paper examines the molecular effects of varying estradiol doses on estrogen receptor enhancers in breast cancer cells, finding distinct biological outcomes at low versus high doses.

This study identifies ASTER-B as a mediator of intracellular estradiol retention in breast cancer cells, which supports estrogen receptor-dependent gene expression and cell growth.

This paper identifies a PARP14/TARG1-regulated MARylation cycle that controls stress granule dynamics and translation in ovarian cancer cells, with potential therapeutic implications.