Tadashi Takeuchi

The paper identifies functional divergence in gut Clostridia from Hadza hunter-gatherers, revealing diet-adapted metabolic pathways that influence gut ecology.

The paper introduces MIG-Seq to analyze IgA binding to gut microbiome strains and finds that microbial genes, especially mucus degradation genes, predict IgA binding levels.

The paper develops improved mouse models of the small intestine microbiota using region-specific human intestinal sampling and in vitro culturing, showing increased diversity and reproducibility in colonization.