Author

Le Yang

Shandong First Medical UniversityORCID 0000-0003-1706-5241Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Le Yang2 papers · Agency for Science, Technology and Research

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

Bo Liu· 1 shared Boran LiiD· 1 shared Changgui LiiD· 1 shared Daiguan Yu· 1 shared Jiahao ZhengiD· 1 shared Jianxin Du· 1 shared Jiayou ZhangiD· 1 shared Jigang LiiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCell Biology

Bo Liu

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2 papers

Recent·Most cited

Cancer BiologyeLifePeer-reviewedDec 27, 2024

TIPE drives a cancer stem-like phenotype by promoting glycolysis via PKM2/HIF-1alpha axis in melanoma

Maojin Tian, Le Yang, Ziqian Zhao…·Peiqing Zhao

This study shows TIPE promotes glycolysis and stemness in melanoma by interacting with PKM2 and activating HIF-1α through phosphorylation.

DOI 10.7554/elife.92741.4

humanproteomics

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Cell BiologyPLoS ONEPeer-reviewedDec 16, 2024

Tumorigencity decrease in Bcl-xL deficient MDCK cells ensuring the safety for influenza vaccine production

Jiahao Zheng, Boran Li, Lanxin Jia…·Changgui Li

The paper knocks out Bcl-xL in MDCK cells to reduce tumorigenicity, creating a safer cell line for influenza vaccine production.

1 citation

mousegenetic perturbation / CRISPR

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