Author
University of OxfordORCID 0000-0003-1806-0952Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Sven Turkalj, Bilyana Stoilova, Angus Groom…·Paresh Vyas
This study shows that resistant clones are rapidly selected in hematopoietic cell compartments with leukemic stem cell potential before relapse in patients treated with ivosidenib combination therapy.
Niels Asger Jakobsen, Sven Turkalj, Andy G. X. Zeng…·Paresh Vyas
This study identifies how DNMT3A and TET2 mutations in hematopoietic stem cells confer a selective advantage by reducing inflammation and aging effects.
Douglas RA Silveira, Prodromos Chatzikyriakou, Pilar Casares Aláez…·Lynn Swun Quek
This study shows that IDH2 mutations in AML block differentiation by altering H3K27 methylation, and that Enasidenib can reverse this block by modulating chromatin states.