Author

Sven Turkalj

University of OxfordORCID 0009-0002-3377-1170Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:differential expression· 3 Organism:human· 3 Assay:scRNA-seq· 3 Approach:statistical model· 3 Assay:ATAC-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:multiome· 2

Frequent Co-Authors

Niels Asger JakobseniD· 3 shared Paresh VyasiD· 3 shared Andy G. X. ZengiD· 2 shared Batchimeg UsukhbayariD· 2 shared Bilyana StoilovaiD· 2 shared Eugenia Flores-Figueroa· 2 shared John E. DickiD· 2 shared Marlen MetzneriD· 2 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

Niels Asger JakobsenORCID

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3 papers

Recent·Most cited

Cancer BiologyBloodPeer-reviewedNov 5, 2025

Rapid clonal selection within early hematopoietic cell compartments presages outcome to ivosidenib combination therapy

Sven Turkalj, Bilyana Stoilova, Angus Groom…·Paresh Vyas

This study shows that resistant clones are rapidly selected in hematopoietic cell compartments with leukemic stem cell potential before relapse in patients treated with ivosidenib combination therapy.

5 citations

humanscRNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintSep 12, 2023

Selective advantage of mutant stem cells in clonal hematopoiesis occurs by attenuating the deleterious effects of inflammation and aging

Niels Asger Jakobsen, Sven Turkalj, Andy G. X. Zeng…·Paresh Vyas

This study identifies how DNMT3A and TET2 mutations in hematopoietic stem cells confer a selective advantage by reducing inflammation and aging effects.

DOI 10.1101/2023.09.12.557322

humanscRNA-seq

𝕏 PostBluesky

Cell BiologybioRxivPreprintSep 11, 2023

Identification of a human hematopoietic stem cell subset that retains memory of inflammatory stress

Andy G.X. Zeng, Murtaza S. Nagree, Niels Asger Jakobsen…·Stephanie Z. Xie

The paper identifies a human HSC subset with inflammatory memory that accumulates with age and clonal hematopoiesis, potentially increasing cancer and infection risks.

DOI 10.1101/2023.09.11.557271

humanscRNA-seq

𝕏 PostBluesky