Jonathan Boulais

This study compares the impact of SARS-CoV-2 variants on host cell RNA and RNA binding protein distribution, finding Omicron causes less disruption and maintains higher expression of translation factors.

The paper investigates how multiple FGFR1 mutations affect tumorigenic mechanisms in glioneuronal tumors by analyzing their interactomes and functional impacts.

This study investigates how inhibiting sphingomyelinases affects extracellular vesicle cargo sorting in human cells, revealing distinct impacts on RNA and protein content and cellular behavior.

The paper shows that localized mRNA translation at cell junctions is essential for epithelial cell polarity, with MAGOH and ZO-1 linked to good prognosis in ovarian cancer.

This study shows GAS6 and AXL reduce insulin sensitivity by altering insulin signaling and increasing insulin receptor trafficking to endosomes.

The paper maps the interactome of ARF and ARL proteins using BioID, identifies new localizations, and reveals functional roles of ARL14 in activating PLD1 and cargo trafficking.

The paper identifies C1orf112 as a novel regulator of interstrand crosslinks that decreases FIGNL1-RAD51 interaction, impairing homology-directed repair.

This study identifies APOBEC2 as a transcriptional repressor that represses non-myogenesis pathway genes to facilitate proper myoblast differentiation.

The paper investigates how different PGC-1α isoforms regulate hepatic metabolism and apoptosis in response to inflammation, identifying distinct roles for PGC-11 and PGC-14.