Author

Esmee Vringer

Cancer Research UK Scotland InstituteORCID 0000-0003-2083-8567Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Catherine CloixiD· 2 shared Rosalie HeiligiD· 2 shared Sara R. ZanivaniD· 2 shared Sérgio LillaiD· 2 shared A. R. S. BlackiD· 1 shared Alba Roca-PortolesiD· 1 shared Alfredo E. Montes-GómeziD· 1 shared Alfredo Montes Gomes· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCell Biology

Catherine CloixORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintSep 22, 2026

RNF213 M1-ubiquitinates damaged mitochondria to activate pro-inflammatory NF-κB signaling

Rosalie Heilig, Hannah Glover, Charlotte E. L. Mellor…·Stephen WG Tait

This study identifies RNF213 as an E3 ligase that catalyzes M1-linked ubiquitination of damaged mitochondria, activating pro-inflammatory NF-κB signaling through NEMO recruitment.

DOI 10.64898/2026.09.21.752888

experimental assay

𝕏 PostBluesky

Cell BiologyThe EMBO JournalPeer-reviewedFeb 9, 2024

Mitochondrial outer membrane integrity regulates a ubiquitin-dependent NF-κB inflammatory response

Esmee Vringer, Rosalie Heilig, Joel S. Riley…·Stephen W. G. Tait

This study shows that mitochondrial outer membrane permeabilization triggers ubiquitin-dependent NF-κB inflammation by recruiting NEMO to ubiquitylated mitochondria.

55 citationstop 2%

experimental assayhost-pathogen & immune response

𝕏 PostBluesky