Author

A. R. S. Black

Cancer Research UK Scotland InstituteORCID 0009-0001-1082-8034Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Ajitha RajaniD· 1 shared Alan SerrelsiD· 1 shared Alexander E.P. LoftusiD· 1 shared Alfredo E. Montes-GómeziD· 1 shared Aurore AguadoiD· 1 shared Catherine CloixiD· 1 shared Colin SmithiD· 1 shared Daniel J. MurphyiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperImmunology

Ajitha RajanORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintNov 26, 2025

FAK inhibitor treatment systemically regulates the glioblastoma immune environment via blocking monocyte trafficking

Emily R. Webb, A. R. S. Black, Giovana Carrasco…·Valerie G. Brunton

This study shows that systemic FAK inhibition reduces immunosuppressive macrophages in glioblastoma by blocking monocyte trafficking, enhancing T cell activity and improving survival in a mouse model.

DOI 10.1101/2025.11.26.690731

mousebulk RNA-seq

𝕏 PostBluesky

Cell BiologyThe EMBO JournalPeer-reviewedFeb 9, 2024

Mitochondrial outer membrane integrity regulates a ubiquitin-dependent NF-κB inflammatory response

Esmee Vringer, Rosalie Heilig, Joel S. Riley…·Stephen W. G. Tait

This study shows that mitochondrial outer membrane permeabilization triggers ubiquitin-dependent NF-κB inflammation by recruiting NEMO to ubiquitylated mitochondria.

55 citationstop 2%

experimental assayhost-pathogen & immune response

𝕏 PostBluesky