Haley Garbus

This study shows formate reduces ischemic injury in male hearts by increasing protein S-nitrosation and preserving BH4 levels through a NOS-dependent mechanism.

This study shows GSNOR deletion protects male cardiac function with age but may worsen female cardiac function by removing an age-related SNO imbalance.

This study shows formate reduces ischemic injury in female ADH5-/- hearts but not in intact female or ovariectomized WT hearts, suggesting estrogen-dependent formate utilization in OCM is critical for cardioprotection.

This study shows that gestational arsenic exposure increases postpartum heart size and disrupts calcium handling in cardiomyocytes.

This study shows that prenatal arsenic exposure reduces maternal cardiac growth and alters gene expression in late pregnancy, potentially contributing to cardiovascular disease.