Jiwon Shim

This study examines mitochondrial metabolism in Drosophila hemocytes across developmental stages and immune states, showing that mitochondrial respiration is key under homeostasis and that immune activation enhances metabolic flexibility and mitochondrial remodeling.

This study identifies S-nitrosylation as a mechanism that maintains hematopoietic progenitor quiescence by inducing the unfolded protein response and blocking receptor function.

The paper investigates how polo regulates cell fate in Drosophila hematopoietic progenitors after ionizing radiation, showing polo suppresses lok to prevent cell death.

The paper creates a single-cell transcriptomic atlas of the adult fruit fly, identifying over 250 cell types and analyzing gene signatures and sexual dimorphism across tissues.

This study shows that odor exposure in Drosophila larvae increases systemic GABA and blood-progenitor Sima levels, enhancing lamellocyte induction and immune response efficiency.

The paper uses single-cell RNA sequencing to analyze myeloid blood cell lineages in Drosophila, identifying novel cell types and lineage dynamics during immune responses.