Author

Alice Decombe

Centre National de la Recherche ScientifiqueORCID 0000-0003-2422-2655Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Étienne DecrolyiD· 2 shared Adrià SoguesiD· 1 shared Brenda W. BontesiD· 1 shared Bruno CanardiD· 1 shared Clara C. PosthumaiD· 1 shared Eric J. SnijderiD· 1 shared François FerróniD· 1 shared Jennifer P. RichardsoniD· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMicrobiology

Étienne DecrolyORCID

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2 papers

Recent·Most cited

MicrobiologyEMBO ReportsPeer-reviewedOct 20, 2023

Tick-borne flavivirus NS5 antagonizes interferon signaling by inhibiting the catalytic activity of TYK2

Ségolène Gracias, Maxime Chazal, Alice Decombe…·Nolwenn Jouvenet

This study identifies a mechanism by which tick-borne flaviviruses inhibit interferon signaling by targeting TYK2 catalytic activity through their NS5 protein.

28 citations

humanproteomics

𝕏 PostBluesky

Molecular BiologyProceedings of the National Academy of SciencesPeer-reviewedNov 29, 2021

Structure-function analysis of the nsp14 N7-guanine methyltransferase reveals an essential role in Betacoronavirus replication

Natacha S. Ogando, Priscila El Kazzi, Jessika C. Zevenhoven-Dobbe…·Eric J. Snijder

This study identifies critical residues in the nsp14 N7-MTase domain essential for betacoronavirus replication and suggests potential drug targets.

56 citations

statistical model

𝕏 PostBluesky