Nolwenn Jouvenet

This study identifies POWV NS5 as a central inhibitor of cytokine signaling by targeting TYK2 and suppressing multiple antiviral pathways.

This study identifies the nuclear localization and interactome of TBEV NS5 protein, revealing its role in modulating viral replication through interactions with nuclear factors.

This study investigates BANAL-236, a SARS-CoV-2-related bat virus, showing it can use human entry factors and evade human innate immunity, suggesting potential for zoonotic spillover.

This study identifies IFI6 as a key antiviral effector mediating type I and III interferon restriction of tick-borne orthoflaviviruses in human cells and mice.

This study investigates YFV-induced stress granules, revealing their enrichment in mitochondrial proteins and their role in mitochondrial dysfunction during infection.

This study shows that Hepatitis E Virus (HEV) ORF2 protein modulates plasmacytoid dendritic cell (pDC)-mediated antiviral responses by affecting pDC recognition of infected cells.

This study identifies a mechanism by which tick-borne flaviviruses inhibit interferon signaling by targeting TYK2 catalytic activity through their NS5 protein.

The paper identifies a virus-encoded microRNA in SARS-CoV-2 that targets interferon-stimulated genes to suppress the host immune response.