Christian Hinze

This study shows that Tolvaptan reduces medullary cell stress and inflammation in kidney injury models.

The paper identifies three epithelial cyst types in ADPKD using single-nucleus RNA sequencing and machine learning, showing their association with therapeutic response.

This study identifies Ilf2 as a key regulator of kidney epithelial stress resilience through transcriptional and splicing programs in cultured cells and mouse models.

This paper develops CORA-T cells to selectively eliminate alloreactive B cells and prevent antibody-mediated rejection in solid organ transplantation.

This study shows that CEP83 deficiency in hiPSCs disrupts intermediate mesoderm differentiation, leading to impaired kidney progenitor formation and increased LPM marker expression.

This study uses urinary single-cell RNA sequencing to analyze injury and repair processes in acute kidney injury, identifying distinct cellular and molecular dynamics.

This study uses single-nuclei transcriptomics to analyze human kidney injury responses, identifying four injury-associated cell states and showing similar gene expression changes between AKI patients with and without COVID-19.