David H. Murray

This study determines the structural morphology and formation of the human exocyst complex, revealing an extended architecture with minimal intersubunit interaction and a single nucleation site.

The paper shows electrostatic changes in the Exo70 subunit led to its dissociation from the exocyst complex, enabling functional divergence in plants.

This study shows that CDK1 phosphorylates PAR-3 in asymmetrically dividing cells, affecting polarity and fate determination in Drosophila neuroblasts and sensory organ precursors.

This paper introduces recombinant biosensors with SNAP tags for multiplex and super-resolution imaging of all 8 phosphoinositides in fixed cells and tissues.