Christian Klotz

This study identifies a complex male fertilization apparatus in Cryptosporidium, essential for infection, and shows that disrupting HAP2 prevents fertilization and clears infection.

This study reveals how Cryptosporidium remodels its single rhoptry into the host interface during invasion and intracellular parasitism.

This study shows human airway organoids can effectively model BSL-4 virus replication and pathogenesis, offering a safe and relevant alternative to animal models.

This study shows that arginine metabolism, specifically through the enzyme ADI, is essential for encystation in Giardia duodenalis, with functional differences between human-specific and zoonotic sub-assemblages.

The paper uses whole genome sequencing to identify three distinct populations of Cryptosporidium parvum, showing the emergence and spread of a European population to the USA.

This study shows Giardia's ventral disc contracts during attachment, causing host cell damage, and identifies three contraction types that reduce disc size.

This study shows that Giardia's ventral disc, shaped by MBP, is essential for attachment and causing host epithelial barrier damage.