Rodrigo Ledesma‐Amaro

This study uses adaptive laboratory evolution to optimize a yeast co-culture chassis for bioproduction, showing improved growth and production performance compared to monocultures.

This paper benchmarks signal peptide-mediated protein translocation in Komagataeibacter rhaeticus to enable in situ functionalization of bacterial nanocellulose during biosynthesis.

PromoterAtlas uses a transformer model to predict regulatory sequences in Gammaproteobacteria, showing cross-species recognition of promoters and sigma factors.

This study demonstrates a synthetic Yarrowia lipolytica consortium that efficiently converts lignocellulosic oligosaccharides into lipids, with division-of-labor strategies outperforming multifunctional monocultures.

This study shows that splitting the violacein production pathway between two E. coli subpopulations increases violacein production by 2.5 times compared to monoculture.

This study reprograms Yarrowia lipolytica metabolism to produce itaconic acid at high titres in bioreactors, offering a safer alternative to pathogenic fungal producers.

This paper identifies DELLA proteins as co-activators that recruit the Mediator subunit MED15 to facilitate transcription in land plants, showing conservation from Arabidopsis to liverworts.

This study uses carbon dots to enhance photosynthesis in cyanobacteria and plants, increasing CO2 fixation and growth rates.

This study engineers Saccharomyces cerevisiae to produce 3-hydroxypropionic acid and succinic acid from glucose-rich lignocellulosic wood hydrolysates under low pH conditions, increasing production titers significantly.

This paper develops an RNA-based feedback control system to stabilize microbial consortia composition without using toxins or syntrophy.

This paper demonstrates the bioconversion of cellulose into bisabolene, a biojet fuel candidate, using rumen bacteria and non-conventional yeast in a sequential bioprocess.

The paper develops a Golden Gate Assembly platform (RtGGA) for Rhodotorula toruloides to enhance metabolic pathway engineering, resulting in a 41% increase in carotenoid production.

The paper develops a modular toolset to improve the performance and standardization of electrogenetic systems for spatiotemporal gene expression control.