Author
Columbia UniversityORCID 0000-0003-2704-9763Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Paul V. Dellorusso, Melissa A. Proven, Fernando J. Calero‐Nieto…·Emmanuelle A. Passegue
This study shows autophagy compensates for inflammation-induced metabolic issues in old HSCs, and temporarily boosting autophagy can restore their function.
Amélie Collins, James W. Swann, Melissa A. Proven…·Emmanuelle A. Passegue
The paper shows maternal IL-10 restricts fetal HSPCs from activating emergency myelopoiesis, leading to reduced myeloid cell production and neonatal neutropenia.
Michael V. Zuccaro, Jia L. Xu, Carl A. Mitchell…·Dieter M. Egli
The paper evaluates Cas9-induced repair outcomes at the EYS locus in human embryos, showing microhomology-mediated end joining restores reading frames without mosaicism, while unrepaired breaks lead to chromosome loss.