Amelia M. Lias

This paper designs a malaria vaccine immunogen using structure-guided methods to present a single epitope from PfRH5, showing improved antibody response in rats compared to PfRH5 alone.

The paper characterizes human antibodies against PfRH5, identifies key features of potent inhibitors, and demonstrates their prophylactic potential against malaria.

This paper develops a stabilized RH5 VLP vaccine that induces improved anti-malarial antibodies compared to a soluble protein vaccine in preclinical studies.

This study designs an improved PvDBP-based immunogen using structure-guided methods to enhance its stability and antibody response against Plasmodium vivax.

This paper develops a combination malaria vaccine targeting the RCR-complex by fusing epitopes from RIPR to CyRPA, improving in vitro growth inhibition compared to RH5.1 alone.