Doris Quinkert

The paper identifies synergistic antibody interactions against the malaria protein RIPR, showing how combinations of antibodies targeting specific domains inhibit parasite invasion.

The paper identifies synergistic non-neutralizing antibodies against PfRH5 that enhance malaria parasite growth inhibition when combined with neutralizing antibodies.

This paper designs a malaria vaccine immunogen using structure-guided methods to present a single epitope from PfRH5, showing improved antibody response in rats compared to PfRH5 alone.

The paper characterizes human antibodies against PfRH5, identifies key features of potent inhibitors, and demonstrates their prophylactic potential against malaria.

This paper develops a stabilized RH5 VLP vaccine that induces improved anti-malarial antibodies compared to a soluble protein vaccine in preclinical studies.

This study designs an improved PvDBP-based immunogen using structure-guided methods to enhance its stability and antibody response against Plasmodium vivax.

This paper develops a combination malaria vaccine targeting the RCR-complex by fusing epitopes from RIPR to CyRPA, improving in vitro growth inhibition compared to RH5.1 alone.

This study evaluates the precision of the Plasmodium knowlesi growth inhibition assay for Plasmodium vivax Duffy-binding protein-based malaria vaccine development, finding significant assay-to-assay variation in %GIA and GIA50.