Margaret Alexander

This study shows that β-hydroxybutyrate (BHB) reduces Th17 cells and SFB abundance, increasing susceptibility to enteric infection by altering gut microbiota.

The paper identifies a female-enriched gut bacterium, Eggerthella lenta, that drives neuroinflammation and IFN-γ via TLR2 in autoimmune disease models.

This study shows gut bacteria produce lactate that increases lung epithelial mitochondrial activity and worsens acute lung injury.

This study shows that a ketogenic diet reduces autoimmune disease in mice by altering host metabolism and shaping gut microbiota, specifically through β-hydroxybutyrate and Lactobacillus species.

This study shows that methotrexate, a non-antibiotic drug, alters the human gut microbiota, favoring Firmicutes over Bacteroidetes, which correlates with improved drug response in rheumatoid arthritis patients.