Author

Dinendra L. Abeyawardhane

University of Maryland, BaltimoreORCID 0000-0003-3002-7792Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1

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Approach:experimental assay· 1

Frequent Co-Authors

Alejandro X. Spittel· 1 shared Amédée des GeorgesiD· 1 shared David J. WeberiD· 1 shared Edwin V. PozharskiiD· 1 shared Izza F. Nawaz· 1 shared Kaylin A. AdipietroiD· 1 shared Kristen M. VarneyiD· 1 shared Mary E. CookiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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1 shared paperBiophysics

Alejandro X. Spittel

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1 paper

Recent·Most cited

BiophysicsbioRxivPreprintAug 18, 2023

Membrane binding and pore formation is Ca2+-dependent for the Clostridioides difficile binary toxin

Dinendra L. Abeyawardhane, Spiridon E. Sevdalis, Kaylin A. Adipietro…·David J. Weber

This study shows that Ca2+ dissociation from CDTb's RBD1 triggers pore formation in endosomal membranes, differing from other binary toxins that rely on pH changes.

DOI 10.1101/2023.08.18.553786

experimental assay

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