Author

Spiridon E. Sevdalis

University of Maryland, BaltimoreORCID 0009-0009-7846-1177Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:phylogenetics / evolution· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Abdu F. AzadiD· 1 shared Alejandro X. Spittel· 1 shared Amédée des GeorgesiD· 1 shared Cassia Brockway· 1 shared Darin L. Shrewsberry· 1 shared David J. WeberiD· 1 shared Dinendra L. AbeyawardhaneiD· 1 shared Edwin V. PozharskiiD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenomics

Abdu F. AzadORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintAug 18, 2023

Membrane binding and pore formation is Ca2+-dependent for the Clostridioides difficile binary toxin

Dinendra L. Abeyawardhane, Spiridon E. Sevdalis, Kaylin A. Adipietro…·David J. Weber

This study shows that Ca2+ dissociation from CDTb's RBD1 triggers pore formation in endosomal membranes, differing from other binary toxins that rely on pH changes.

DOI 10.1101/2023.08.18.553786

experimental assay

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GenomicsPeerJPeer-reviewedDec 17, 2020

Evolution of Wolbachia Mutualism and Reproductive Parasitism: Insight from Two Novel Strains that Co-infect Cat Fleas

Timothy Driscoll, Victoria I. Verhoeve, Cassia Brockway…·Joseph J. Gillespie

The paper reports the genomes of two novel Wolbachia strains co-infecting cat fleas, revealing lateral gene transfers and mechanisms for mutualism and reproductive parasitism.

73 citationstop 1%

DNA methylationwhole-genome sequencing

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