Author

Guillaume Darrasse-Jèze

InsermORCID 0000-0003-3069-8211Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Guillaume Darrasse-Jèze1 paper

Biology Disciplines

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Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Katrina PodsypaninaiD· 2 shared Paul RégnieriD· 2 shared Bénédicte ManouryiD· 1 shared Cecilia EstrellaiD· 1 shared David KlatzmanniD· 1 shared Djamel Nehar-BelaidiD· 1 shared Encarnita Mariotti‐FerrandiziD· 1 shared Gwladys FourcadeiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersImmunology

Katrina PodsypaninaORCID

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintJan 18, 2026

Toll-like receptor 9 contributes in microglial activation and lysosomal dysfunction to promote Alzheimer disease

Moïse de Lavergne, Lucie Mazzola, Katrina Podsypanina…·Bénédicte Manoury

This study identifies TLR9's role in microglial activation and lysosomal dysfunction in Alzheimer's disease, showing its inhibition reduces pathology and cognitive defects.

DOI 10.64898/2026.01.16.699962

𝕏 PostBluesky

Cancer BiologybioRxivPreprintJun 18, 2024

Application of the AMOCATI R workflow to tumor transcriptomic data delineates the adverse effect of immune cell infiltration in immune-privileged organs

Paul Régnier, Nicolas Cagnard, Katrina Podsypanina, Guillaume Darrasse-Jèze

The paper uses the AMOCATI R workflow to analyze tumor transcriptomic data and shows that immune cell infiltration has adverse effects in immune-privileged organs but beneficial effects in non-privileged organs.

DOI 10.1101/2024.06.18.596859

humanbulk RNA-seq

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ImmunologybioRxivPreprintSep 7, 2023

Tissue-resident uterine regulatory T cells support fetal growth

Laura V. Flórez, Gwladys Fourcade, Guillaume Darrassse-Jèze…·David Klatzmann

The paper identifies uterine tissue-resident regulatory T cells (uTregs) that support fetal growth by promoting uterine remodeling and vascular development during pregnancy.

2 citations

mousebulk RNA-seq

𝕏 PostBluesky