Thibaut Sanchez

This study uncovers distinct roles of RIAM and Lpd in osteoclast fusion and resorption through differential Rap1-Talin1 signaling, showing that disrupting the direct Rap1-Talin1 interaction reduces bone resorption and increases bone mass.

This study identifies moesin's role in osteoclast fusion and function, showing its impact on bone resorption and disease therapy.

This study shows that ezrin, radixin, and moesin are not required for macrophage migration or actin cortex mechanics, challenging their universal importance in these processes.