Author

Jacob M. Majikes

National Institute of Standards and TechnologyORCID 0000-0003-3177-4941Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Assay:electrophysiology· 1 Approach:experimental assay· 1 Approach:statistical model· 1 Research Focus:synaptic & neural circuits· 1

Frequent Co-Authors

J. Alexander LiddleiD· 2 shared Adam L. PintariD· 1 shared Amna Hasni· 1 shared Arvind K. BalijepalliiD· 1 shared Joseph W. F. RobertsoniD· 1 shared Michael P. ZwolakiD· 1 shared Seulki ChoiD· 1 shared Shankar Haridas· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 21 mutual co-author links

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2 shared papersBiophysics

J. Alexander LiddleORCID

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2 papers

Recent·Most cited

BiophysicsNucleic Acids ResearchPeer-reviewedJan 15, 2026

Complex cooperativity in DNA origami revealed via design dependent defectivity

Jacob M. Majikes, Amna Hasni, Shankar Haridas…·J. Alexander Liddle

The paper explores cooperativity in DNA origami by analyzing design variations and their impact on assembly yield, identifying metrics that correlate with defectivity and yield.

DOI 10.1093/nar/gkag052

statistical model

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BioengineeringNanoscalePeer-reviewedJan 1, 2024

Variable Gain DNA Nanostructure Charge Amplifiers for Biosensing

Jacob M. Majikes, Seulki Cho, Thomas E. Cleveland…·Arvind K. Balijepalli

This paper demonstrates DNA nanostructures that amplify electrochemical biosensing signals through conformational changes, achieving a 2x104-fold response enhancement independent of analyte-DNA interactions.

3 citations

electrophysiologyexperimental assay

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