Bing Xia

The paper shows that defective BRCA1-mediated DNA end resection leads to Group 1 tandem duplication formation and FANCM synthetic lethality in mouse models.

This study shows EHMT1 and EHMT2 have distinct roles in cancer therapy, with EHMT1 affecting DNA replication and alkylating agents, while EHMT2 influences immunotherapy response via STING expression.

This study shows that PALB2 maintains redox and mitochondrial homeostasis in the brain and works with ATG7 to prevent p53-dependent neurodegeneration.

The paper develops a high-resolution peptide-protein docking method called PIPER-FlexPepDock, validated on known complexes to show accuracy and efficiency.