Cory M. Hogaboam

The paper identifies senescent fibroblast heterogeneity in IPF and links it to DNA damage response dysregulation using gene expression analysis.

This study shows that cellular senescence in IPF fibroblasts disrupts antiviral responses, leading to increased viral titers and altered inflammation.

This study shows that syndecan-1 promotes AT2 cell senescence in lung fibrosis, contributing to fibrotic remodeling and suggesting it as a therapeutic target.

This study identifies LPCAT1 as a critical regulator of AT2 cell renewal and lipid metabolism in IPF, showing that reactivating LPCAT1 can mitigate lung fibrosis.

This study evaluates the anti-fibrotic effects of LTI-03 in IPF patient-derived precision cut lung slices, showing dose-dependent reduction of fibrotic markers.

This study shows that the CSD peptide LTI-2355 improves phagocytic and reduces pro-inflammatory activity in myeloid cells from IPF and PASC-F patients.