Shirin Nouraein

This paper introduces a platform called INTACT that non-invasively monitors specific mRNA levels in vivo by using synthetic serum markers and RNA-based sensors.

This study uses synthetic serum markers (RMAs) to monitor retinal gene expression and cell survival through blood tests, showing high sensitivity and non-destructiveness.

This paper introduces erasable serum markers (ESMs) to improve the sensitivity and temporal resolution of brain gene expression monitoring through blood tests.

This study demonstrates that AAV9.retro can safely and efficiently deliver genes to neuronal projections noninvasively using FUS-BBBO, offering improved specificity compared to invasive methods.

This study uses acoustically targeted chemogenetics to non-invasively increase seizure threshold in mice by inhibiting hippocampal pyramidal neurons.

This paper introduces a noninvasive method to monitor brain gene expression using engineered reporters called RMAs, which detect neuronal activity through blood measurements.

This paper introduces RAID, a noninvasive method to control specific brain cell types using ultrasound and enzyme-prodrug pairs for sustained neuromodulation.