Author

Xiaoying Jian

National Cancer InstituteORCID 0000-0003-3556-0553Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:simulation· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

Alexander J. SodtiD· 2 shared Eric RosenbergiD· 2 shared Olivier SoubiasiD· 2 shared Paul A. RandazzoiD· 2 shared R. Andrew ByrdiD· 2 shared Rebekah A. JacksoniD· 2 shared Benjamin J. Hu· 1 shared Di XiaiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersBiochemistry

Alexander J. SodtORCID

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2 papers

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedSep 30, 2025

The PH domain in the ArfGAP ASAP1 drives catalytic activation through an unprecedented allosteric mechanism

Olivier Soubias, Samuel L. Foley, Xiaoying Jian…·R. Andrew Byrd

The study reveals an allosteric mechanism by which the PH domain of ASAP1 enhances Arf1 GTPase activity through structural and dynamic interactions on a membrane surface.

2 citations

structural biologyexperimental assay

𝕏 PostBluesky

BiochemistryPLoS ONEPeer-reviewedApr 4, 2024

Point mutations in Arf1 reveal cooperative effects of the N-terminal region and myristate for GTPase-activating protein catalytic activity

Eric Rosenberg, Xiaoying Jian, Olivier Soubias…·Paul A. Randazzo

The paper investigates how point mutations in Arf1 affect its interaction with GAPs, revealing cooperative effects between the N-terminal region and myristate on catalytic activity.

1 citation

experimental assayprotein folding & dynamics

𝕏 PostBluesky