Author

Sara Peffer

The University of Texas Health Science Center at HoustonORCID 0000-0003-3788-5044Unclaimed ORCID profile · follow to get notified of new preprints

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Cell Biology· 1

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Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Organism:yeast· 1

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D. L. Goncalves· 1 shared Duong Long DuyiD· 1 shared Kevin A. MoranoiD· 1 shared

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2024-2024 · peak 1/yr

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1 shared paperCell Biology

D. L. Goncalves

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1 paper

Recent·Most cited

Cell BiologyMolecular Biology of the CellPeer-reviewedFeb 21, 2024

Cytoplasmic redox imbalance in the thioredoxin system activates Hsf1 and results in hyperaccumulation of the sequestrase Hsp42 with misfolded proteins

D. L. Goncalves, Duong Long Duy, Sara Peffer, Kevin A. Morano

This study shows that disrupting the cytosolic thioredoxin system in yeast activates Hsf1 and causes Hsp42 to hyperaccumulate with misfolded proteins, leading to growth defects under oxidative stress.

8 citations

yeastproteomics

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