Author

Filippo Artoni

Leiden University Medical CenterORCID 0000-0003-3902-9217Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Constantinos DemetriadesiD· 2 shared Stephanie FernandesiD· 2 shared Adam AntebiiD· 1 shared Almut Nebel· 1 shared Andreas BeyeriD· 1 shared Anna R. Diederich· 1 shared Antonios PapadakisiD· 1 shared Birgit Gerisch· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersGenetics

Constantinos DemetriadesORCID

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3 papers

Recent·Most cited

GeneticsbioRxivPreprintMay 28, 2026

Rare genetic variants in the IIS/mTOR signalling pathway identified in exceptionally long-lived individuals show shared in vitro effects associated with lifespan across species

Mara Neuerburg, Larissa Smulders, Erik B. van den Akker…·Joris Deelen

This study identifies rare genetic variants in the IIS/mTOR pathway in long-lived humans and shows they have shared functional effects on lifespan-related traits in mice.

DOI 10.64898/2026.05.28.728260

mouseexperimental assay

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GeneticsbioRxivPreprintApr 14, 2025

Resilience and restoration from fasting-refeeding mediated by a nutrient-regulated linker histone

Kazuto Kawamura, Anna R. Diederich, Birgit Gerisch…·Adam Antebi

The paper shows that hil-1/H1-0, a nutrient-regulated linker histone, mediates resilience and restoration during fasting-refeeding in C. elegans and human cells.

2 citations

C. eleganshuman

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Cell BiologyNature Cell BiologyPeer-reviewedOct 9, 2024

Spatially and Functionally Distinct mTORC1 Entities Orchestrate the Cellular Response to Amino Acid Availability

Stephanie Fernandes, Danai-Dimitra Angelidaki, Julian Nüchel…·Constantinos Demetriades

This study reveals spatially and functionally distinct mTORC1 entities that regulate cellular responses to amino acid availability through lysosomal and non-lysosomal mechanisms.

73 citationstop 1%

humangenetic perturbation / CRISPR

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