Sharon E. Bickel

This study shows that Sirt1 maintains meiotic cohesion in Drosophila oocytes, and preserving its activity during aging reduces chromosome segregation errors.

This study shows that autophagy decline in aging Drosophila oocytes leads to cohesion loss and segregation errors during meiosis.

This study shows that cohesin turnover and new linkage formation occur during meiotic prophase in Drosophila oocytes, independent of Smc3 acetylation.

The paper identifies proteins required for cohesion rejuvenation during meiotic prophase in Drosophila oocytes using an RNAi screen, finding Brahma and Pumilio as key regulators.