Luka Čičin‐Šain

The paper identifies TBKBP1 as a key gene whose demethylation enhances cytotoxic activity in CMV-specific CD8+ T cells, suggesting it as a therapeutic target.

This paper develops a method to detect epistatic interactions in SARS-CoV-2 genomes using mutual information, demonstrating its ability to identify key interactions in real-time from large sequence datasets.

This study develops ARMATA, a method to measure antiviral T-cell activity against HCMV, revealing pp65 antigen recognition occurs before the late virus cycle phase.

The paper identifies ZAP-S as a host protein that inhibits SARS-CoV-2 programmed ribosomal frameshifting, reducing viral replication.

The paper shows that effector memory T-cells (TEM) proliferate during persistent CMV infection, maintaining memory inflation, while central memory T-cells (TCM) do not proliferate as much.