Renée Z. Wang

This paper designs novel Rubisco variants using protein language models, identifying active candidates with improved CO2/O2 specificity and structural validity.

This paper measures temperature-dependent kinetic isotope effects (KIEs) in two rubisco forms, showing their KIEs decrease linearly with temperature, impacting interpretations of carbon isotope variations in Earth and biological sciences.

The paper maps the sequence-to-function relationship of rubisco by assaying single amino acid mutants in E. coli, identifying conserved positions and mutations that improve CO2 affinity.

The paper identifies a Prochlorococcus lineage in oxygen deficient zones that expresses both form I and form II rubiscos, suggesting an adaptation to low oxygen environments.

The paper identifies flavohemoglobin as a detoxifying NO reductase that imparts a distinct isotopic fingerprint on N2O under anoxia, suggesting a new framework for attributing N2O sources.