James A. McCormick

This study investigates how Eln haploinsufficiency affects kidney handling of water and electrolytes through vasopressin receptor signaling and finds sex-dependent disruptions in sodium and water reabsorption.

This study uses a knock-in mouse model to analyze native ENaC complexes in different tissues, revealing tissue-specific differences in channel abundance and complex size.

This study investigates how ovarian hormones affect blood pressure differences in female Eln haploinsufficient mice, finding that ovariectomy alters diastolic blood pressure and sodium retention mechanisms.

The paper uses snRNA-seq to analyze DCT cells, revealing distinct functional subtypes DCT1 and DCT2 with different gene expression patterns and developmental origins.