David H. Ellison

This study uses a knock-in mouse model to analyze native ENaC complexes in different tissues, revealing tissue-specific differences in channel abundance and complex size.

This study shows that kidney kallikrein-1 contributes to gamma-ENaC cleavage but is not essential for overall ENaC function or electrolyte balance.

This study shows NRBP1 and TSC22D proteins modulate WNK signaling in the kidney's distal convoluted tubule, affecting Na+ reabsorption through NCC phosphorylation.

The paper identifies three distinct cell types in thick ascending limb cells across species, each with unique potassium channel and claudin expression patterns that influence cation transport.

The paper uses snRNA-seq to analyze DCT cells, revealing distinct functional subtypes DCT1 and DCT2 with different gene expression patterns and developmental origins.